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. 2017 Dec 1;10(1):13–21. doi: 10.14740/jocmr3209w

Table 4. Effect of Vitamin D Supplementation and Low-Fat Milk Intake on Each Biomarker.

Baseline to 3 months
Baseline to 6 months
CON (n = 10) MKD (n = 10) P CON (n = 10) MKD (n = 10) P
25(OH)D (ng/mL)
  Model 1 -6.33 ± 0.76 -0.32 ± 0.76 < 0.01 -6.12 ± 0.78 -2.21 ± 0.78 < 0.01
  Model 2 -6.17 ± 0.83 -0.48 ± 0.83 < 0.01 -5.87 ± 0.85 -2.45 ± 0.85 0.02
  Model 3 -6.19 ± 0.96 -0.46 ± 0.96 < 0.01 -5.46 ± 0.95 -2.87 ± 0.95 0.11
PTH (pg/mL)
  Model 1 1.17 ± 1.50 -3.87 ± 1.50 0.03 9.91 ± 2.53 3.59 ± 2.53 0.10
  Model 2 2.01 ± 1.53 -4.71 ± 1.53 0.01 9.67 ± 2.77 3.83 ± 2.77 0.18
  Model 3 1.63 ± 1.65 -4.33 ± 1.65 0.04 7.32 ± 2.43 6.18± 2.43 0.77
TNF-α (pg/mL)
  Model 1 0.03 ± 0.08 -0.11 ± 0.08 0.25 -0.07 ± 0.08 -0.19 ± 0.08 0.36
  Model 2 0.04 ± 0.10 -0.12 ± 0.10 0.35 -0.10 ± 0.10 -0.16 ± 0.10 0.71
  Model 3 -0.03 ± 0.08 -0.05 ± 0.08 0.94 -0.10 ± 0.11 -0.16 ± 0.11 0.77
CTX (ng/mL)
  Model 1 -0.13 ± 0.04 -0.13 ± 0.04 0.95 -0.10 ± 0.09 -0.09 ± 0.09 0.92
  Model 2 -0.15 ± 0.04 -0.12 ± 0.04 0.60 -0.14 ± 0.09 -0.05 ± 0.09 0.50
  Model 3 -0.14 ± 0.04 -0.13 ± 0.04 0.86 -0.15 ± 0.09 -0.04 ± 0.09 0.44
BAP (µg/L)
  Model 1 0.31 ± 1.58 -0.53 ± 1.58 0.71 0.85 ± 1.39 0.33 ± 1.39 0.80
  Model 2 -0.18 ± 1.72 -0.04 ± 1.72 0.96 0.90 ± 1.54 0.29 ± 1.54 0.80
  Model 3 0.25 ± 2.01 -0.47 ± 1.96 0.82 1.05 ± 1.77 0.13 ± 1.77 0.75

Values are represented as mean ± SE. The change in concentration of each biomarker in both groups was compared after each biomarker was adjusted for Baseline values, frequency of menses, and running distance, respectively. Model 1: baseline value. Model 2: baseline value, frequency of menses (baseline value). Model 3: baseline value, frequency of menses (baseline value), running distance (baseline value). MKD: vitamin D supplement + low-fat milk group; CON: control group.