Table 4. Effect of Vitamin D Supplementation and Low-Fat Milk Intake on Each Biomarker.
Baseline to 3 months |
Baseline to 6 months |
|||||
---|---|---|---|---|---|---|
CON (n = 10) | MKD (n = 10) | P | CON (n = 10) | MKD (n = 10) | P | |
25(OH)D (ng/mL) | ||||||
Model 1 | -6.33 ± 0.76 | -0.32 ± 0.76 | < 0.01 | -6.12 ± 0.78 | -2.21 ± 0.78 | < 0.01 |
Model 2 | -6.17 ± 0.83 | -0.48 ± 0.83 | < 0.01 | -5.87 ± 0.85 | -2.45 ± 0.85 | 0.02 |
Model 3 | -6.19 ± 0.96 | -0.46 ± 0.96 | < 0.01 | -5.46 ± 0.95 | -2.87 ± 0.95 | 0.11 |
PTH (pg/mL) | ||||||
Model 1 | 1.17 ± 1.50 | -3.87 ± 1.50 | 0.03 | 9.91 ± 2.53 | 3.59 ± 2.53 | 0.10 |
Model 2 | 2.01 ± 1.53 | -4.71 ± 1.53 | 0.01 | 9.67 ± 2.77 | 3.83 ± 2.77 | 0.18 |
Model 3 | 1.63 ± 1.65 | -4.33 ± 1.65 | 0.04 | 7.32 ± 2.43 | 6.18± 2.43 | 0.77 |
TNF-α (pg/mL) | ||||||
Model 1 | 0.03 ± 0.08 | -0.11 ± 0.08 | 0.25 | -0.07 ± 0.08 | -0.19 ± 0.08 | 0.36 |
Model 2 | 0.04 ± 0.10 | -0.12 ± 0.10 | 0.35 | -0.10 ± 0.10 | -0.16 ± 0.10 | 0.71 |
Model 3 | -0.03 ± 0.08 | -0.05 ± 0.08 | 0.94 | -0.10 ± 0.11 | -0.16 ± 0.11 | 0.77 |
CTX (ng/mL) | ||||||
Model 1 | -0.13 ± 0.04 | -0.13 ± 0.04 | 0.95 | -0.10 ± 0.09 | -0.09 ± 0.09 | 0.92 |
Model 2 | -0.15 ± 0.04 | -0.12 ± 0.04 | 0.60 | -0.14 ± 0.09 | -0.05 ± 0.09 | 0.50 |
Model 3 | -0.14 ± 0.04 | -0.13 ± 0.04 | 0.86 | -0.15 ± 0.09 | -0.04 ± 0.09 | 0.44 |
BAP (µg/L) | ||||||
Model 1 | 0.31 ± 1.58 | -0.53 ± 1.58 | 0.71 | 0.85 ± 1.39 | 0.33 ± 1.39 | 0.80 |
Model 2 | -0.18 ± 1.72 | -0.04 ± 1.72 | 0.96 | 0.90 ± 1.54 | 0.29 ± 1.54 | 0.80 |
Model 3 | 0.25 ± 2.01 | -0.47 ± 1.96 | 0.82 | 1.05 ± 1.77 | 0.13 ± 1.77 | 0.75 |
Values are represented as mean ± SE. The change in concentration of each biomarker in both groups was compared after each biomarker was adjusted for Baseline values, frequency of menses, and running distance, respectively. Model 1: baseline value. Model 2: baseline value, frequency of menses (baseline value). Model 3: baseline value, frequency of menses (baseline value), running distance (baseline value). MKD: vitamin D supplement + low-fat milk group; CON: control group.