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. 2017 Nov 3;7(11):e017732. doi: 10.1136/bmjopen-2017-017732

Table 4B.

Relationship between CTS severity and MHQ subscales

n Overall function
Mean (SD)
Estimate (95% CI)* ADL unilateral
Mean (SD)
Estimate (95% CI)* ADL bilateral
Mean (SD)
Estimate (95% CI)* Work
Mean (SD)
Estimate (95% CI)*
CTS-6 score
 1.00 7 92.1 (10.7) 91.4 (16.5) 88.8 (11.4) 92.9 (12.9)
 1.01–2.00 134 68.5 (20.3) 82.9 (22.0) 82.9 (18.9) 78.7 (22.3)
 2.01–3.00 308 58.3 (19.1) 74.5 (23.1) 76.2 (20.7) 70.7 (22.8)
 3.01–4.00 241 44.9 (18.9) 56.8 (26.3) 60.7 (24.9) 55.0 (23.2)
 4.01–5.00 63 25.8 (16.2) −14.7 (−16.4 to −13.1) 28.2 (26.4) −17.8 (−19.9 to −15.8) 38.3 (26.2) −14.6 (−16.4 to −12.8) 39.6 (22.2) −13.4 (−15.4 to −11.5)
p<0.0001 p<0.0001 p<0.0001 p<0.0001
R2=41.1% R2=40.7% R2=40.8% R2=33.3%
NCS grade
 1 150 58.9 (23.9) 71.0 (27.9) 72.7 (24.4) 63.9 (27.4)
 2 79 53.5 (22.9) 71.5 (27.7) 74.1 (25.2) 67.5 (26.2)
 3 202 54.6 (22.8) 70.5 (27.7) 72.6 (24.6) 65.8 (26.0)
 4 137 53.1 (20.5) 67.0 (26.3) 68.2 (24.3) 63.4 (23.9)
 5 159 48.8 (21.2) 57.8 (30.0) 63.5 (27.3) 64.4 (24.4)
 6 24 43.3 (24.9) −3.16 (−3.56 to −1.22) 47.9 (29.8) −3.87 (−5.32 to −2.42) 52.5 (26.0) −3.16 (−4.42 to −1.90) 61.9 (23.6) −0.86 (−2.18 to 0.47)
p<0.0001 p<0.0001 p<0.0001 p=0.197
R2=15.5% R2=18.7% R2=21.9% R2=15.7%

*Parameter estimate (95% CI) from a linear model including gender, age, ethnicity, employment status, smoking status, units of alcohol per week, body mass index, duration of CTS and comorbidity score.

ADL, activities of daily living; CTS, carpal tunnel syndrome; MHQ, Michigan Hand Questionnaire; NCS, nerve conduction studies.