Table 1.

Cost parameters, their sources and ranges for sensitivity analyses

	Resource	Cost (€*), mean	Cost (€*), SD	Source	Distribution
	ICU bed-day	1583	226	AP-HP	Gamma
Universal strategies
Hand hygiene	Alcohol-based hand rub	0.011	0.0055	47 48	Gamma
	HCW’s time per hand hygiene	0.143	0.0714	47	Gamma
	Infection control nurse at half-time/month†	2048‡	164	AP-HP	Gamma
Antibiotic stewardship	Infectious disease physician at half-time/month†	5500‡	273	AP-HP	Gamma
Targeted strategies
Screening	Screening test+laboratory costs	40	20	48–50	Gamma
Contact precautions (=hand hygiene at 80%/80% with identified ESBL-PE patients)	Alcohol-based hand rub	0.011	0.0055	47 48	Gamma
	HCW’s time per hand hygiene	0.143	0.0714	47	Gamma
Cohorting (additional HCW+contact precautions)	Additional full-time HCW/month†	3598‡	642	AP-HP	Gamma
	Alcohol-based hand rub	0.011	0.0055	47 48	Gamma
	HCW’s time per hand hygiene	0.143	0.0714	47	Gamma

Costs of control strategies were based on material and personnel. For example, the cost of the HH improvement strategy included the cost of HH (hand rub and HCWs’ time) and the cost of an infection control nurse working on the programme, that is, HH education, observation and feedback.

*€1=US$0.94.

†Assumption based on expert opinion.

‡Cost of staff from a hospital perspective (salary+employer contributions).

AP-HP, Assistance Publique-Hôpitaux de Paris; ESBL-PE, extended-spectrum beta-lactamase-producing Enterobacteriaceae; HCWs, healthcare workers; HH, hand hygiene; ICU, intensive care unit.