Table 7.
No | Study | MAST | p Value | PNC | CEST | CENC | METR | EER | p Value | CNTM | ||||||
1 | 2 | 3 | 4 | 5 | 6 | 7 | ||||||||||
1 | Brandes153 | 10.15 (9.24–11.06) | 0.943 | 6 | 9.64 | 4 | 1.20 (0.74–1.95) | 1.01 | 0.979 | ∞ | 2.56 | 1.59 | 0.99 | 1.65 | 1.59 | 91 |
2 | Strik155 | 8.40 (7.52–9.29) | 0.015 | 6 | 7.98 | 4 | 0.81 (0.44–1.48) | 0.68 | 0.302 | −2.56 | ∞ | 4.22 | 1.62 | 4.63 | 4.19 | −2.64 |
3 | Abacioglu156 | 7.34 (6.46–8.22) | <0.001 | 6 | 6.98 | 4 | 0.57 (0.37–0.89) | 0.48 | 0.016 | −1.59 | −4.22 | ∞ | 2.62 | −47.9 | 592 | −1.62 |
4 | Berrocal157 | 5.63 (4.76–6.51) | <0.001 | 6 | 5.35 | 3 | 0.19 (0.08–0.49) | 0.16 | <0.001 | −0.99 | −1.62 | −2.62 | ∞ | −2.48 | −2.63 | −1.00 |
5 | WA (1–4) | 7.44 (6.56–8.31) | <0.001 | 6 | 7.07 | 4 | 0.59 (0.40–0.88) | 0.50 | 0.015 | −1.65 | −4.63 | 47.9 | 2.48 | ∞ | 44.3 | −1.68 |
6 | WA (2–4)* | 7.34 (6.46–8.21) | <0.001 | 6 | 6.97 | 4 | 0.57 (0.39–0.85) | 0.48 | 0.011 | −1.59 | −4.19 | −592 | 2.63 | −44.3 | ∞ | −1.62 |
7 | Sahinbas23 | 10.10 (9.10–11.10) | 1.000 | 6 | 9.5 | 4 | 1.19 (0.59–2.40) | 1.00 | 1.000 | −91 | 2.64 | 1.62 | 1.00 | 1.68 | 1.62 | ∞ |
*Main comparator.
CA, coefficient of attenuation; CENC, cost-effective number of cycles; CEST, cost-effective survival time; EER, effect enhancement rate; MAST, maximal attainable survival time; METR, median effect-to-treatment ratio; WA, weighted average; PNC, peak number of cycles.