Table 5.
Parameter | Hazard Ratio (95% Confidence Interval) | P valuea,c |
---|---|---|
PCI (versus no PCI) | 0.471 (0.24–0.93) | 0.0300 |
Age (1-year increase) | 0.912 (0.82–1.02) | 0.1007 |
Male (versus female) | 1.478 (0.84–2.61) | 0.1752 |
Performance Score | 0.8472 | |
PS 1 (versus PS 0) | 0.909 (0.46–1.79) | 0.7837b |
PS 2 (versus PS 0) | 1.078 (0.49–2.38) | 0.8525b |
Stage | 0.3757 | |
(>1 metastatic site) versus (0 or 1 metastatic site) | 1.268 (0.75–2.14) | 0.3744b |
Response: CR (versus no CR) | 0.698 (0.34–1.44) | 0.3241 |
Likelihood ratio P value from a Cox model, stratified by study.
Wald P values.
Significant values are in bold
CR, complete response; ESCLC, extensive small-cell lung cancer; LSCLC, limited small-cell lung cancer; PCI, prophylactic cranial irradiation.