TABLE V. Activity of the isolated compounds 1-7 on intracellular amastigote forms of Leishmania (Viannia) braziliensis, Vero and THP-1 cell lines.
| Sample | L. (V.) braziliensis IC50 (µM) | THP-1 IC50 (µM) | Vero IC50 (µM) |
|---|---|---|---|
| 1 | 21.4 | > 200 | > 200 |
| 2 | 28.3 | > 200 | > 200 |
| 3 | > 200 | > 200 | > 200 |
| 4 | 78.5 | > 200 | > 200 |
| 5 | 24.8 | > 200 | > 200 |
| 6 | > 200 | > 200 | > 200 |
| 7 | 72.6 | > 200 | > 200 |
| Amphotericin B | 0.12 | 12.0 | 18.2 |