Fig. 2. (A) rhodamine 123 uptake and accumulation mean fluorescence intensity (MFI) with or without verapamil blockade in Leishmania infantum promastigotes. Statistical analysis was performed by Kruskal-Wallis test. Results are the mean ± standard error of the mean (SEM) of three independent experiments. (B) Promastigote viability after exposure to SbIII for 48 h with or without verapamil blockade. Each isolate was exposed to its own IC50. Statistical analysis was performed by ANOVA with Tukey's post-test. Statistical significance was defined in p < 0.05. Data shown are from two independent experiments performed in quintuplicate. SbS: antimony sensitive isolate; SbR: antimony resistant isolate.
