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. 2017 Nov 29;17:667–679. doi: 10.1016/j.nicl.2017.11.023

Table 1.

Clinical characteristics and classification using logistic regression with exhaustive feature selection and cross-validation of near-term DTI compared to near-term structural MRI findings, in VLBW preterm children who scored below one SD (< 1SD) versus equal to or greater than one SD (≥ 1SD) below mean BSID-III cognitive and motor score. MRI findings include presence of white matter abnormality (WMA), cerebellar signal abnormality, and cerebellar asymmetry.


BSID-III cognitive composite
BSID-III motor composite
BSID-III fine motor
BSID-III gross motor
< 1SD ≥ 1SD < 1SD ≥ 1SD < 1SD ≥ 1SD < 1SD ≥ 1SD
Total (N) 8 51 10 50 11 49 15 45
GA-at-birth (days, mean [SD]) 187.75 [13.27] 203.22 [16.07] 196.10 [15.81] 202.44 [16.52] 199.64 [16.82] 201.78 [16.49] 197.87 [17.24] 202.56 [16.17]
Birth weight (g, mean [SD]) 925.00 [247.02] 1089.51 [261.72] 1021.80 [271.13] 1075.14 [261.27] 985.73 [268.21] 1084.33 [259.25] 1006.73 [303.12] 1086.09 [245.98]
PMA-at-scan (g, mean [SD]) 258.50 [9.07] 255.69 [9.01] 254.20 [6.85] 256.24 [9.44] 255.00 [10.25] 256.10 [8.79] 257.33 [9.29] 255.42 [8.97]
Prediction using DTI-based logistic regression with LOOCV 8/8 51/51 8/10 48/50 11/11 43/49 14/15 30/45
Prediction using WMA identified on structural MRI (N/total) 0/8 47/51 1/10 47/50 0/11 45/49 1/15 42/45
Prediction using cerebellar signal abnormality identified on structural MRI (N/total) 2/8 45/51 2/10 44/50 2/11 43/49 3/15 40/45
Prediction using cerebellar asymmetry identified on structural MRI (N/total) 1/8 47/51 1/10 46/50 0/11 44/49 1/15 41/45