Figure 2. Effects of ERβ on Apoptosis of TNBC cells.
A. and B. A protein-based apoptosis array was used to assess the effects of 1 nM E2 treatment (24 hours) of ERβ expressing MDA-MB-231 cells on the expression levels of multiple pro- and anti-apoptotic proteins. C. and D. Annexin V staining of MDA-MB-231-ERβ cells following 24 hours and 5 days of treatment with vehicle, 1 nM estrogen or 10 nM LY500307 as determined by flow cytometry.