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. 2017 May 27;8(57):96753–96760. doi: 10.18632/oncotarget.18239

Table 1. Characteristics of never users and ever users of sitagliptin.

Variable Never users (n = 39195) Ever users (n = 39195) P-value SD
n % n %
Age (years) 55.81 ± 10.16 56.19 ± 9.97 < 0.0001 3.83
Diabetes duration (years) 6.60 ± 2.74 6.63 ± 2.79 0.1764 0.53
Sex (men) 21331 54.42 21282 54.30 0.7253 −0.16
Hypertension 30121 76.85 30434 77.65 0.0077 1.90
Chronic obstructive pulmonary disease 16590 42.33 16639 42.45 0.7232 0.20
Stroke 9056 23.10 9086 23.18 0.7994 0.14
Nephropathy 8821 22.51 8940 22.81 0.3100 0.81
Ischemic heart disease 14965 38.18 14881 37.97 0.5367 −0.37
Peripheral arterial disease 8005 20.42 8162 20.82 0.1658 1.09
Eye disease 12766 32.57 12785 32.62 0.8849 0.12
Obesity 2955 7.54 2826 7.21 0.0779 −1.47
Dyslipidemia 32800 83.68 32978 84.14 0.0836 1.39
Acute pancreatitis 198 0.51 201 0.51 0.8803 0.10
Tobacco abuse 1405 3.58 1491 3.80 0.1034 1.21
Alcohol−related diagnoses 2134 5.44 2071 5.28 0.3179 −0.68
Gingival and periodontal diseases 35017 89.34 34974 89.23 0.6195 −0.38
Oral mucosal lesions 866 2.21 841 2.15 0.5407 −0.53
Statin 27403 69.91 27767 70.84 0.0044 2.11
Fibrate 16169 41.25 16420 41.89 0.0689 1.47
Angiotensin converting enzyme inhibitor/angiotensin receptor blocker 27046 69.00 27534 70.25 0.0002 2.68
Calcium channel blocker 20072 51.21 20550 52.43 0.0006 2.47
Sulfonylurea 21967 56.05 23149 59.06 < 0.0001 5.85
Metformin 29817 76.07 30018 76.59 0.0912 0.82
Insulin 2350 6.00 2186 5.58 0.0121 −2.23
Acarbose 4444 11.34 4257 10.86 0.0335 −1.60
Pioglitazone 2588 6.60 2577 6.57 0.8742 0.22
Rosiglitazone 1770 4.52 1453 3.71 < 0.0001 −4.07
Aspirin 21560 55.01 21938 55.97 0.0066 1.89
Ticlopidine 1253 3.20 1323 3.38 0.1608 0.99
Clopidogrel 3098 7.90 3016 7.69 0.2748 −0.81
Dipyridamole 12029 30.69 12387 31.60 0.0058 2.10

Age and diabetes duration are expressed as mean ± standard deviation

SD: standardized difference