Table 4. Univariate and multivariate analyses for the predictor of progression to CRPC using genetic analysis.

	Univariate		Multivariate
	HR (95% CI)	p-value	HR (95% CI)	p-value
Age, yr	0.959 (0.919–1.000)	0.050	1.016 (0.951–1.084)	0.644
PSA	1.001 (1.001–1.002)	< 0.001	1.000 (0.998–1.001)	0.815
Biopsy Gleason score
6	ref		ref
7	0.384 (0.024–6.177)	0.500	0.457 (0.028–7.531)	0.584
8	6.483 (0.870–48.299)	0.068	7.670 (0.932–63.088)	0.058
rs2241714	0.516 (0.246–1.084)	0.081	1.702 (0.572–5.066)	0.339
rs143790069	1.590 (0.600–4.214)	0.351	0.666 (0.163–2.730)	0.573
rs72821581	1.573 (0.475–5.214)	0.459	1.170 (0.283–4.837)	0.828
rs75992542	1.593 (0.644–3.945)	0.314	2.825 (0.685–11.656)	0.151
rs56350726	2.734 (1.215–6.155)	0.015	4.172 (1.223–14.239)	0.023

Multivariate Cox model including Age, PSA, biopsy Gleason score, rs2241714, rs143790069, rs72821581, rs75992542, rs56350726