Table 2. Parasite proteins observed uniquely in EgHF.
| Serial No. | Band nos. | Sum of emPAI1 | Description | Accession no.2 (EgrG_) | Mouse homolog3 | Principal functions |
|---|---|---|---|---|---|---|
| 1 | 3-5 | 0.63 | ECP | 000378300 | - | Not-available |
| 2 | 3 | 0.28 | ECP | 000956500 | - | Not-available |
| 3 | 3 | 0.22 | SOD1 | 000638300 | P08228 | Antioxidant |
| 4 | 3 | 0.26 | Profilin | 000122100 | - | Actin binding |
| 5 | 4 | 1.86 | ECP | 000079500 | - | Not-available |
| 6 | 5, 6 | 1.62 | Ferritin | 000382200 | P09528 | Iron transport |
| 7 | 5 | 0.2 | snRNP | 000525910 | - | Isomerase |
| 8 | 6 | 2.08 | ECP | 000596300 | - | Not-available |
| 9 | 6 | 1.29 | ECP | 000315600 | - | Not-available |
| 10 | 6 | 0.35 | ThioTrx | 000791700 | P35700 | Redox homeostasis |
| 11 | 6-10 | 1.42 | PI16 | 000766600 | P49935 | Protease inhibitor |
| 12 | 7 | 0.16 | Niemann Pick | 000682900 | Q9Z0J0 | Lipid metabolism |
| 13 | 7 | 0.13 | Complement TNF | 001189200 | Q8R2Z0 | Carbohydrate metabolism |
| 14 | 7 | 0.12 | TPI | 000416400 | P17751 | Carbohydrate metabolism |
| 15 | 8 | 0.57 | 14-3-3 protein | 000789700 | P16054 | Signaling |
| 16 | 8 | 0.26 | IoMT | 001133400 | P23506 | Transferase |
| 17 | 8 | 0.1 | PGM | 000799500 | O70250 | Carbohydrate metabolism |
| 18 | 10, 11 | 1.52 | MDH | 001185000 | P08249 | Carbohydrate metabolism |
| 19 | 10 | 0.31 | LDHA | 000660800 | P06151 | Carbohydrate metabolism |
| 20 | 10, 11 | 0.4 | Succinyl CoA syn | 001199000 | Q9Z2I8 | Ligase |
| 21 | 10 | 0.23 | IGBP | 000799300 | P05017 | Signaling |
| 22 | 10 | 0.29 | Transaldolase | 000092800 | Q93092 | Carbohydrate metabolism |
| 23 | 10 | 0.08 | PDH | 000956200 | O70571 | Carbohydrate metabolism |
| 24 | 12 | 1.15 | OA | 001032200 | P29758 | Transferase |
| 25 | 13 | 1.54 | Citrate synthase | 001028500 | Q9CZU6 | Carbohydrate metabolism |
| 26 | 13 | 0.4 | NADPH | 001068500 | P54071 | Carbohydrate metabolism |
| 27 | 13 | 0.25 | PDHE1 | 000590700 | P35486 | Carbohydrate metabolism |
| 28 | 13 | 0.12 | Acyl CoA HT | 001087900 | Q9DBK0 | Lipid metabolism |
| 29 | 14, 15 | 1.21 | Calnexin | 000875100 | P35564 | Chaperone |
| 30 | 14 | 0.27 | Iron:zinc AP | 001169400 | Q8BX37 | Hydrolase |
| 31 | 14 | 0.12 | GD | 000589100 | P26443 | Oxidoreductase |
| 32 | 16 | 1.33 | VAT | 000317300 | Q8BRU6 | Transport |
| 33 | 16 | 0.06 | Lysyl oxidase | 000217900 | P58022 | Oxidoreductase |
| 34 | 16 | 0.12 | AspRNA | 000777100 | Q922B2 | Protein biosynthesis |
| 35 | 17, 19 | 1.21 | PEPCK | 000292700 | Q8BH04 | Carbohydrate metabolism |
| 36 | 20 | 0.07 | Macroglobulin | 000641200 | Q3UU35 | Serine protease inhibitor |
| 37 | 21 | 0.05 | Collagen α1(XV) | 000729300 | O35206 | ECM |
| 38 | 22 | 0.04 | Hemicentin 1 | 000422350 | D3YXG0 | Cell cycle |
1Exponentially modified protein abundance index.
2Accession numbers were obtained from NCBInr DB (http://www.ncbi.nlm.nih.gov/) and E. granulosus DB (http://www.genedb.org/Homepage/Egranulosus).
3Mouse homologs were retrieved using Uniprot software (http://www.uniprot.org/).
Acyl CoA HT, acyl coenzyme A hydrolase transferase; AspRNA, aspartyl tRNA synthetase cytoplasmic; Complement TNF, complement C1q tumor necrosis factor; ECP, expressed conserved protein; FABP, fatty acid binding protein; FGFR, fibroblastic growth factor receptor; GD, glutamate dehydrogenase; GST, glutathione transferase; IoMT, protein l isoaspartate o methyltransferase; Iron:zinc AP, iron:zinc purple acid phosphatase; IGBP, insulin growth factor binding protein; LDHA, lactate dehydrogenase A; LDLR, low density lipoprotein receptor protein; MDH, malate dehydrogenase (mitochondrial); NAALAD2, N-acetylated alpha-linked acidic dipeptidase 2; NADPH, NADPH dependent isocitrate dehydrogenase; Niemann-Pick, Niemann Pick C2 protein; OA, ornithine aminotransferase; PDH, pyruvate dehydrogenase; PDHE1, PD E1 component subunit; PEPCK, phosphoenolpyruvate carboxykinase; PGM, phosphoglycerate mutase; PI16, peptidase inhibitor 16; snRNP, U snRNP cyclophilin; SOD1, superoxide dismutase 1 (soluble); Succinyl CoA syn, succinyl coenzyme A synthetase α subunit; TPI, triosephosphate isomerase; ThioTrx, thioredoxin peroxidase; VAT, vesicular amine transporter.