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. 2017 Oct 13;8(57):97187–97205. doi: 10.18632/oncotarget.21907

Figure 3. Salidroside restores skeletal muscle cells proliferation and migration potentials suppressed by hyperglycemia.

Figure 3

(A, B) The percentage of proliferative C2C12 cells treated with salidroside and cultured under hyperglycemia, as analyzed using Ki67 staining: (A) representative images (scale bars: 200 μm); and (B) quantification of the ratio of Ki67 positive cells to DAPI positive cells. (C) The number of C2C12 cells treated with salidroside and cultured under hyperglycemia, as analyzed using crystal violet staining. (D, E) The migration potential of C2C12 cells treated with salidroside and cultured under hyperglycemia, as examined using transwell chamber assay: (D) representative images (scale bars: 100 μm); and (E) quantification of migrated cells. All experiments were done under hypoxia. Data shown are representative from three independent experiments. Quantification data were expressed as mean ± S.D. (n = 6). **P < 0.01; SA: salidroside.