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. 2017 Oct 26;8(57):97407–97415. doi: 10.18632/oncotarget.22129

Table 2. Clinicopathologic features of the four groups.

Clinicopathologic features Group 1
(n=45)
Group 2
(n=40)
Group 3
(n=174)
Group 4
(n=39)
Univariate Analysis
F/χ2/H P value
Sex, n (%)
 Male 7(15.6) 4(10.0) 71(40.8) 11(28.2) 21.144 0.000*
 Female 38(84.4) 36(90.0) 103(59.2) 28(71.8)
Age (years)
 Mean ± SD 38.36±13.35 33.38±10.46 41.76±10.91 36.38+10.51 7.516 0.000*
Tumor size (cm)
 Median (range) 1.0(0.6-1.5) 1.4(0.7-2.2) 1.0(0.7-1.5) 0.9(0.5-1.5) 7.121 0.068
Tumor multifocality, n (%)
 No 19(42.2) 18(45.0) 77(44.3) 17(43.6) 0.081 0.994
 Yes 26(57.8) 22(55.0) 97(55.7) 22(56.4)
Tumor lesion, n (%)
 Unilateral 33(73.3) 32(80.0) 106(60.9) 23(59.0) 7.234 0.065
 Bilateral 12(26.7) 8(20.0) 68(39.1) 16(41.0)
Extracapsular invasiveness, n (%)
 No 18(40.0) 24((60.0) 69(39.7) 20(51.3) 6.622 0.085
 Yes 27(60.0) 16(40.0) 105(60.3) 19(48.7)
TNM-Stage, n (%)
 I 28(62.2) 32(80.0) 103(59.2) 32(82.1) 12.976 0.164
 II 0(0) 0(0) 2(1.1) 0(0)
 III 8(17.8) 4(10.0) 28(16.1) 3(7.7)
 IV 9(20.0) 4(10.0) 41(23.6) 4(10.3)
131I dose
 Median (range) 100(30-150) 60(30-150) 30(30-150) 30(30-30) 21.293 0.000*
Ps-Tg level (ng/mL)
 Median (range) 0.1(0.1-1.5) 0.3(0.1-1.9) 2.1(0.6-7.0) 1.9(0.7-6.3) 35.987 0.000*
Ps-TSH level (μIU/mL)
 Median (range) 100.0(73.2-138.4) 130.5(86.5-150.0) 100.0(75.7-129.3) 103.3(75.3-137.5) 6.520 0.089

*P<0.05; Ps-Tg, preablative-stimulated thyroglobulin; Ps-TSH: preablative thyroid stimulating hormone.