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. 2007 Jul 17;8(3):37–51. doi: 10.1120/jacmp.v8i3.2320

Table 1.

Modified Radiation Therapy Oncology Group grading criteria

Acute genitourinary Acute gastrointestinal
Grade 1 Requiring no medication Requiring no medication
Grade 2 Frequency of urination or nocturia less frequent than every hour, dysuria, urgency, bladder spasm requiring local anesthetic Diarrhea requiring parasympatholytic drugs; mucous discharge not necessitating sanitary pads; rectal or abdominal pain requiring narcotic analgesics
Grade 3 Frequency with urgency and nocturia hourly or more frequently, dysuria, pelvis pain, or bladder spasm requiring frequent narcotic; gross hematuria with or without clot formation Diarrhea requiring parenteral support; severe mucous or blood discharge necessitating sanitary pads; abdominal distension
Grade 4 Hematuria requiring transfusion; acute bladder obstruction not secondary to clot passage, ulceration, or necrosis Acutre or subacute obstruction, fistula or perforation; gastrointestinal bleeding requiring transfusion; abdominal pain or tenesmus requiring tube decompression or bowel diversion