Figure 3. Quantitative comparison of double labeled motor neurons across groups (Experiment 2).
(A) True Blue (TB) labeling was slightly lower in no-repair (NR) animals and double labeling (DL) was slightly higher in animals treated with cellular scaffolds (CLSC), though these differences were not statistically significant. In general, motor neuron counts were variable across animals in all groups. (B) The percentage of double labeled cells was calculated for each group. These data were corrected to account for axons that had branched off to innervate extrinsic muscle targets prior to the point of secondary labeling. A group effect was noted for these corrected percentages with the CLSC group being significantly different from animals treated with unseeded collagen-laminin scaffolds (CL). Error bars reflect standard deviations across animals for each group. * p < 0.05.