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. Author manuscript; available in PMC: 2017 Dec 9.
Published in final edited form as: Burns. 2017 Jun 8;43(8):1717–1724. doi: 10.1016/j.burns.2017.04.026

Fig. 3.

Fig. 3

Definitive closer of wounds with autologous split-thickness skin grafts is not affected by rejection of preceding GalT-KO grafts, nor allografts. (A) Time course of split-thickness skin graft appearance. Primary (left panel) GalT-KO porcine (upper row) and allografts (lower row) vascularized (early, POD 6) then rejected (late, POD 13) as expected within 14 days. Secondary autologous grafts (right panel) showed evidence of take and vascularization early (POD 2) and all healed to provide definitive wound closure (late, POD 48). Representative images are shown. (B) Mean cosmetic outcome scores for three autologous skin grafts post-GalT-KO and three autologous grafts post-allografts. A panel of blinded observers scored images of autologous grafts from 1 to 10 based upon cosmetic appearance. Statistical significance was determined using the student’s t-test (p=0.40). Two additional grafts are excluded from cosmetic outcome analysis due to technical failure and delayed re-grafting.