Fig. 4.
Correlations between baseline magnetic resonance imaging measurements and changes in cognitive outcomes before and after allopregnanolone treatment. Both correlation of coefficient (r) and coefficient of determination of goodness of fit (R 2) are provided. Shaded areas represent the 95% confidence intervals on the linear regression lines. BDS-2 = Behavioral Dyscontrol Scale; SCL-90-R = Symptom Checklist-90-Revised; HV = hyperintensity volume; OTS MLFC = Cambridge Neuropsychological Test Automated Battery One Touch Stocking mean latency to first choice; CC = corpus callosum; MD = mean diffusivity