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. 2017 Jul 13;14(4):1073–1083. doi: 10.1007/s13311-017-0555-6

Table 3.

Estimated 2-compartment pharmacokinetic parameters

Parameter Estimate Units
V 1.11 l/kg
V2 1.61 l/kg
CLx 2.12 l/h/kg
CL2 1.87 l/h/kg

Tmax = 30 min. Cmax = 35.5 ng/ml. The falling phase was fit to a single exponential with half-time of 34.7 min

V = volume of distribution of central compartment; V2 = volume of distribution of peripheral compartment; CL = central compartment clearance; CL2 = peripheral compartment clearance