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. 2017 Dec 8;11:130. doi: 10.1186/s13065-017-0357-2

Table 21.

Cyclooxygenase inhibition activity of synthesized compound

Compounds Concentration (Um) (no. of experiments) COX-1 activity (% inhibition) COX-2 activity (% inhibition)
71 10 (3) 28.4 ± 11.6 19.4 ± 8.2
72 10 (3) 26.5 ± 6 13.6 ± 1.1
Celecoxib 10 (3) 0.3 ± 2.5 30.8 ± 5.9