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Cytotoxicity of synthesized thiazolidinediones
| Compounds | IC50 (μg/ml) | |||||||
|---|---|---|---|---|---|---|---|---|
| HepG2 | HC-60 | KB | LLC | LNCaP | LU-1 | MCF-7 | SW-480 | |
| 80 | > 100 | 82.2 ± 4.5 | 44.1 ± 3.6 | 87.4 ± 6.3 | 77.4 ± 5.8 | 52.9 ± 3.4 | 66.0 ± 2.7 | 71.4 ± 3.6 |
| 81 | 86.3 ± 6.4 | 75.3 ± 3.9 | 84.6 ± 4.2 | > 100 | 81.6 ± 6.3 | > 100 | 32.8 ± 1.4 | 90.1 ± 4.8 |
| 82 | 78.4 ± 5.8 | 92.3 ± 5.3 | 74.1 ± 5.1 | 90.1 ± 7.7 | 84.2 ± 4.1 | 65.5 ± 4.1 | 52.7 ± 3.6 | 85.4 ± 7.4 |
| Ellipticine | 1.45 ± 0.08 | 0.56 ± 0.04 | 0.43 ± 0.05 | 0.98 ± 0.04 | 0.86 ± 0.06 | 1.29 ± 0.11 | 0.49 ± 0.04 | 0.64 ± 0.05 |
