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. 2017 Dec 8;11:130. doi: 10.1186/s13065-017-0357-2

Table 8.

Evaluation of hypoglycemic activity: effect of compound on % decrease in blood glucose in diabetic mice

Compounds 0 h 2 h 4 h 6 h 24 h
Control 252.53 ± 4.254 4.74 ± 0.68 7.9 ± 4.32 13.43 ± 2.68 3.18 ± 4.35
Piogiltazone 250.75 ± 5.21 31.07 ± 6.74 37.48 ± 5.37 45.41 ± 3.67 10.3 ± 6.53
18 252.79 ± 2.85 29.34 ± 4.53 36.52 ± 5.43 46.64 ± 4.52 6.70 ± 6.51
19 252.19 ± 4.35 24.7 ± 3.97 34.76 ± 6.51 37.89 ± 5.43 5.19 ± 7.74
20 254.38 ± 4.53 26.64 ± 5.28 34.26 ± 5.67 37.05 ± 4.62 4.19 ± 5.43
21 253.60 ± 5.64 22.9 ± 4.72 35.6 ± 5.53 40.41 ± 5.97 3.87 ± 6.53
22 252.73 ± 5.23 29.01 ± 6.54 36.47 ± 4.65 39.21 ± 5.74 3.0 ± 3.75