Figure 4.

Correlations between prefrontal-amygdala connectivity with anxiety and skin conductance response. (A) There was a trend for vmPFC-amygdala connectivity to correlate with skin conductance response (SCR) during extinction recall [SCR was calculated as the difference score (CS+ minus CS–)] in adults r = 0.412, p = 0.162, but not adolescents r = 0.055, p = 0.834. (B) dlPFC-amygdala connectivity correlated with state anxiety symptoms in adolescent participants. There was a positive association between dlPFC-amygdala connectivity and state anxiety in adolescents (r = 0.545, p = 0.024). The association in adults was not significant when a statistical outlier (>3 S.D. below the mean) was included (r = −0.364, p = 0.201) or windsorized (r = −0.511, p = 0.062).