Figure 4.

Blocking by clotrimazole of serum-dependent erythrophagocytosis. RBCs were loaded with 0.5 and 7 μM ionic Ca concentrations in a choline medium, with and without 2 μM clotrimazole. Phagocytosis of loaded cells was determined (in percent) following incubation in RPMI medium without (white and dotted columns) and with 40% AS (black and cross-hatched columns), in the presence (dotted and cross-hatched columns) and absence (white and black columns) of clotrimazole. Cells were treated with the azole throughout the whole experiment. Results from five experiments are shown as mean value ± 1SD of mean. Vertical bars indicate the SD. Asterisks number denotes statistical significance and n.s stands for not significant. See the text for further details.