Table 1.
Quantification of the number of endocrine cells per islet.
| Tissues | N | Number of cells per isleta | |
|---|---|---|---|
| (mean ± SD) | range | ||
| Young control | 11 | 69 ± 25 | 23 to 300 |
| Young CF | 16 | 61 ± 23 | 22 to 280 |
| Histopathologic grade | |||
| 1 and 2 | 6 | 75 ± 20 | 22 to 280 |
| 3 | 5 | 57 ± 18 | 22 to 160 |
| 4 | 3 | 46 ± 21 | 21 to 160 |
| 4 | 1 (CF13) | 35 ± 18b,c | 25 to 80 |
| 5 | 1 (CF16) | 33 ± 16b,c | 21 to 70 |
aNumber of cells per islets represents the number of nucleated synaptophysin-positive cells counted within the cross-sections of the pancreatic islets. Data are mean ± SD of measurements obtained from the indicated number of cases. bRepresents the mean ± SD of measurements obtained from 310 and 180 islets counted in the CF13 and CF16 cases, respectively. c p < 0.01, vs. controls.