Fig. 5.

Overexpression of Kv1.1 enables normal dendritic development of Grin1KO^ThEpor and VPM_IONS neurons. a Kcna1 electroporation enables dendritic development in Grin1KO^ThEpor neurons (P7 Grin1KO^ThEpor + Kcna1^GFP n = 15 from 6 mice). P7 WT and P7 Grin1KO^ThEpor data reported from Fig. 1b and d. Scale bar: 20 μm. b Kcna1 overexpression enables the dendritic development of VPM_IONS neurons (P7 IONS + Kcna1^GFP n = 14 from 7 mice). P7 WT and P7 IONS data reported from Figs. 1b and 4c. Scale bar: 20 μm. c Left: linear model integrating the dendritic complexity parameters described above, using control P2 and P7 conditions as training data sets. Right: summary of the findings. One-way ANOVA with Tukey's post-hoc test for all statistical tests relating to dendritic complexity, except for Sholl analyses for which a two-way ANOVA with Tukey's post-hoc test was used. *P < 0.05, **P < 0.01, ***P < 0.001