Table 2.

Adapted parameters for in-ambulance telemedicine under 12 minutes time gain on average per patient and additional costs.

Parameter				Base-case value		Source/assumption
Probabilities
	After suspected stroke
		Standard care		0.61		Multimedia Appendix 4
		In-ambulance telemedicine		0.39		Multimedia Appendix 4
	After ischemic stroke
		IVTa		0.19		Multimedia Appendix 4
		EVTb		0.07		Multimedia Appendix 4
		Conservative treatment		0.73		Multimedia Appendix 4
	After ischemic stroke and IVT
		0-90 min		0.15		Multimedia Appendix 4
		91-180 min		0.29		Multimedia Appendix 4
		181-270 min		0.56		Multimedia Appendix 4
	After ischemic stroke and EVT
		0-180 min		0.19		Multimedia Appendix 4
		181-270 min		0.23		Multimedia Appendix 4
		271-360 min		0.38		Multimedia Appendix 4
		361-480 min		0.19		Multimedia Appendix 4
Costs, US $ (€)
	Cost per teleconsultation			142.89 (107.52)		Multimedia Appendix 5
	Cost of installation of 1 telemedicine device			29,011 (26,000)		Offer from Zebra Academy
	Estimated total cost for in-ambulance telemedicine for 390 treated patients in 1 year			159,425 (119,959)		Multimedia Appendix 5
Number of patients that can be treated with 1 device in 1 year				150		Activation rates of the PreSSUB-Ic trial [4]

^aIVT: intravenous administration of recombinant tissue plasminogen activator.

^bEVT: endovascular treatment.

^cPreSSUB-I: Prehospital Study at the Universitair Ziekenhuis Brussel I.