Table 3.
Primary and secondary end points
| Outcome | Open necrosectomy after PCD(n = 12) | Percutaneous debridement after PCD (n = 15) |
Risk ratio (95% CI) |
P value |
|---|---|---|---|---|
| Primary composite end point: major complications or death - no. (%)a | 11 (92%) | 8 (53%) | 1.71 (1.04–2.84) | 0.04 |
| Secondary end points | ||||
| Major complication - no. (%) | ||||
| New-onset organ failure | 7 (58%) | 2 (13%) | 4.38 (1.11–17.32) | 0.04 |
| Multiple-organ failure | 3 (25%) | 0 | 0.08 | |
| Intestinal fistula | 6 (50%) | 7 (47%) | 1.07 (0.49–2.34) | 0.86 |
| Intra-abdominal bleeding | 3 (25%) | 1 (7%) | 3.75 (0.45–31.62) | 0.29 |
| Stress ulcer with bleeding | 2 (17%) | 0 | 0.19 | |
| Other outcome | ||||
| Intestinal obstruction | 2 (17%) | 0 | 0.19 | |
| Cerebral infarction | 1 (8%) | 0 | 0.44 | |
| Arrhythmia | 0 | 1 (7%) | 0.27 | |
| Death - no. (%) | 2 (17%) | 0 | 0.19 | |
| Postoperative ICU admission time | 0.02 | |||
| Median | 17 | 0 | ||
| IQR | 7–35 | 0–9 | ||
| Days in hospital | 0.25 | |||
| Median | 62 | 52 | ||
| IQR | 40–73 | 41–60 |
aMultiple events in the same patient were considered as one end point