Table 2.
Natural killer cell activities and cytokine production from PBMCs
| Control group (n = 24) | ICU patient (n = 24) | p | |
|---|---|---|---|
| NK cell activity | |||
| NK cell activity E:T = 10:1 (%)∮ | 27.4 ± 2.37 | 16.4 ± 1.99 | 0.002 |
| NK cell activity E:T = 5:1 (%)∮ | 20.8 ± 1.85 | 13.1 ± 2.15 | 0.006 |
| NK cell activity E:T = 2.5:1 (%)∮ | 20.1 ± 2.20 | 13.0 ± 1.94 | 0.011 |
| NK cell activity E:T = 1.25:1 (%)∮ | 23.1 ± 2.24 | 15.1 ± 2.19 | 0.013 |
| Non-stimulated PBMC | |||
| TNF-α (pg/mL)∮ | 2.03 ± 0.31 | 5.26 ± 1.48 | 0.103 |
| IL-6 (pg/mL)∮ | 12.1 ± 3.57 | 19.9 ± 3.29 | 0.039 |
| IL-1β (pg/mL)∮ | 0.70 ± 0.24 | 2.58 ± 0.51 | 0.002 |
| PBMC (LPS 5 ng/mL) | |||
| TNF-α (pg/mL)∮ | 299.7 ± 42.5 | 173.0 ± 39.2 | 0.007 |
| IL-6 (pg/mL)∮ | 2045.3 ± 341.9 | 685.9 ± 238.8 | 0.025 |
| IL-1β (pg/mL)∮ | 22.5 ± 5.90 | 18.0 ± 6.79 | 0.304 |
| PBMC (LPS 10 ng/mL) | |||
| TNF-α (pg/mL)∮ | 322.3 ± 49.2 | 210.5 ± 57.7 | 0.015 |
| IL-6 (pg/mL)∮ | 2479.2 ± 369.2 | 498.9 ± 108.4 | <0.001 |
| IL-1β (pg/mL)∮ | 24.7 ± 3.77 | 15.2 ± 4.92 | 0.001 |
Mean ± SE.∮tested by logarithmic transformation. p: derived from independent t-test