Table 1.
Demographic and clinical characteristics of patients before and after CPAP therapy (n = 34)
| Variables | Before CPAP | After CPAP | p-value |
|---|---|---|---|
| Age | 55.2 (7.9) | – | – |
| BMI | 31.2 (4.1) | 31.3 (4.0) | 0.901 |
| Smoking | 7 (20.6) | – | – |
| ESS >10 | 8.4 (4.3) | 4.8 (2.7) | <0.001* |
| AHI (events/h) | 35.2 (18.8) | 2.6 (2.3) | <0.001 |
| ODI (events/h) | 25.5 (20.0) | – | – |
| Mean SaO2 (%) | 92.1 (2.1) | – | – |
| Lower SaO2 (%) | 79.8 (8.5) | – | – |
| SaO2 < 90% (%) | 17.7 (18.5) | – | – |
| Total cholesterol, mg/dl | 198.2 (32.9) | 187.4 (36.0) | 0.021 |
| HDL-cholesterol, mg/dl | 44.3 (10.3) | 44.5 (11.0) | 0.678 |
| LDL-cholesterol, mg/dl | 131.0 (29.4) | 121.5 (30.8) | 0.031 |
| Triglycerides, mg/dl | 137.9 (51.0) | 126.6 (59.6) | 0.124 |
| Glucose, mg/dl | 98.7 (12.8) | 98.2 (11.7) | 0.924 |
| HbA1c, % | 5.7 (0.4) | 5.8 (0.4) | 0.064 |
| 24 h SBP (mm Hg) | 129.8 (10.5) | 128.0 (10.3) | 0.287 |
| 24 h DBP (mm Hg) | 82.4 (7.1) | 79.2 (6.4) | 0.004 |
| Pulse pressure (mm Hg) | 47.4 (7.3) | 48.8 (8.1) | 0.050 |
| 24 h MBP (mm Hg) | 97.4 (7.9) | 94.9 (7.2) | 0.030 |
| Day-time SBP (mm Hg) | 133.3 (10.5) | 131.2 (10.9) | 0.214 |
| Day-time DBP (mm Hg) | 85.4 (7.3) | 81.6 (6.9) | 0.001 |
| Night-time SBP (mm Hg) | 117.9 (12.6) | 116.4 (9.5) | 0.363 |
| Night-time DBP (mm Hg) | 72.1 (9.1) | 70.1 (5.9) | 0.169 |
| Hypertension n (%) | 27 (79.4) | 25 (73.5) | 0.500* |
| Antihypertensive drugs, n (%) | 21 (61.8) | – | – |
| Dyslipidaemia n (%) | 28 (82.4) | 24 (70.6) | 0.125* |
| Lipid lowering drugs n (%) | 14 (41.2) | – | – |
| MetS n (%) | 21 (61.8) | 20 (58.8) | 1.000* |
| Cf-PWV (m/s) | 12.3 (2.3) | 11.7 (1.8) | 0.086 |
Results are expressed as mean (standard deviation); *p-values obtained by McNemar test; remaining p-values were obtained by Wilcoxon rank exact test
CPAP continuous positive airway treatment, BMI Body mass index, ESS Epworth Sleepiness Scale, AHI Apnea/Hypopnea Index, ODI Oxygen Desaturation Index, SaO 2 arterial oxygen saturation, HbA1c glycated haemoglobin, SBP systolic blood pressure, DBP diastolic blood pressure, MetS metabolic syndrome, cf-PWV carotid-femoral pulse wave velocity