Table 1.
Patient characteristics before venovenous extracorporeal membrane oxygenation
All (n = 106) |
Survivor (n = 50) |
Non-survivor (n = 56) |
P | |
---|---|---|---|---|
Age (year) | 53 ± 15 | 51 ± 15 | 55 ± 15 | 0.11 |
Male | 71 (67) | 35 (70) | 36 (64) | 0.53 |
Predicted body weighta (kg) | 55 ± 14 | 55 ± 16 | 55 ± 11 | 0.89 |
Hospital day before ECMO | 6 (1–14) | 2(1–9) | 11(4–20) | <0.001* |
Mechanical ventilation before ECMO (day) | 3 (1–9) | 1(0–4) | 6(1–12) | <0.001* |
Cause of ARDS | ||||
Viral pneumonia | 24 (21) | 11 (22) | 13 (23) | 0.88 |
Bacterial pneumonia | 38 (37) | 16 (32) | 22 (39) | 0.54 |
Fungal pneumonia | 3 (3) | 0 | 3 (6) | 0.25 |
Aspiration pneumonitis | 3 (3) | 3 (6) | 0 | 0.10 |
Other acute respiratory diagnoses | 38 (36) | 20 (40) | 18 (32) | 0.40 |
Acute associated infection | 24 (21) | 11 (22) | 13 (23) | 0.88 |
Immunocompromised statusb | 37 (35) | 11 (22) | 26 (46) | 0.008* |
Renal failure requiring dialysis | 28 (26) | 13 (26) | 15 (27) | 0.93 |
Creatinine (mg/dL) | 1.6 (0.8–3.4) | 2.8 ± 3.3 | 2.3 ± 2.3 | 0.36 |
Total bilirubin (mg/dL) | 1.5 ± 2.5 | 1.1 ± b1.2 | 1.9 ± 3.2 | 0.14 |
Platelet count (109/L) | 137 (83–218) | 172 (113–237) | 106 (60–161) | 0.002* |
Hemoglobin (g) | 10 (9–12) | 11 (9–12) | 10 (9–11) | 0.08 |
SOFA score | 10 (8–11) | 9 (7–10) | 10 (9–12) | 0.002* |
RESP score | 2 ± 3 | 2 ± 3 | 1 ± 3 | 0.05* |
Data were presented as mean ± standard deviation in normal-distributed numerical variables, median (interquartile range) in numerical variables not normal-distributed, and n (%) in categorical variables. ECMO Extracorporeal membrane oxygenation, SOFA sequential organ failure assessment, RESP score Respiratory extracorporeal membrane oxygenation survival prediction score, ARDS Acute respiratory distress syndrome. a Ideal body weight is calculated by the ARDSnet formulas. bImmunocompromised status includes hematologic malignancy, solid tumor, solid organ transplantation, liver cirrhosis Child B or C, or autoimmune diseases requiring long-term immunosuppressive therapy
*p < 0.05. (in the comparisons between survivors and non-survivors)