Table 5.

Gene Expression Level Change and Treatment Response

Response Group	Change in CTC Levels from Baseline to Week 8
	Mean	Median	Range	Quartiles	p-value
CK19
Yes (N=21)	− 350	0	−4063 - 865	25%: −1 75%: −204	0.25
No (N=38)	−75	−2	−16,272-11,906	25%: 2 75%: −13
Mammoglobin
Yes (N=21)	− 67	0	−738 - 36.0	25%: 0 75%: −11	0.05
No (N=38)	− 32	0	−970 - 313	25%: 7 75%: − 0.1
Response Group	Change in CTC Levels from Baseline to End of Treatment
	Mean	Median	Range	Quartiles	p-value
CK19
Yes (N=13)	2732	0	−3392 - 39,385	25%: 2 75% −141	0.34
No (N=31)	− 479	0	−15,332 - 999	25%: 10 75%: − 8
Mammoglobin
Yes (N=13)	1176	0	−192 -15,506	25%: 0 75%: −0.6	0.09
No (N=31)	−0.06	0	−970 -1459	25%: 9 75% −0.1