Table 2.
Univariate logistic regression analysis of concealed CRF
| Normal renal function | Concealed CRF | OR | 95% CI | P-value | |
|---|---|---|---|---|---|
| All subjects | |||||
| n | 183 | 29 | |||
| Age, years | 69.11±9.47 | 71.03±8.02 | 1.024 | 0.979–1.070 | 0.302 |
| Gender (male proportion) | 86.89% | 93.10% | 0.491 | 0.110–2.197 | 0.352 |
| Smoking percentage | 54.64% | 72.41% | 2.179 | 0.918–5.173 | 0.078 |
| BMI (kg/cm2) | 22.31±3.18 | 22.62±2.95 | 1.031 | 0.912–1.167 | 0.623 |
| ADAMTS-13 (ng/mL) | 347.05±25.70 | 284.40±21.01 | 0.876 | 0.834–0.920 | <0.001 |
| vWF (ng/mL) | 6.63±2.79 | 8.77±2.67 | 1.331 | 1.135–1.560 | <0.001 |
| MPV (fl) | 10.99±1.10 | 11.36±0.89 | 1.374 | 0.952–1.983 | 0.090 |
| PDW (fl) | 10.60±1.52 | 10.61±1.54 | 1.007 | 0.778–1.302 | 0.960 |
| Fbg (g/L) | 3.16±1.10 | 4.91±2.49 | 1.935 | 1.491–2.512 | <0.001 |
| D-dimer (μg/L) | 293.70 (7.80) | 317.28 (13.12) | 1.146 | 1.097–1.198 | <0.001 |
| IL-6 (pg/mL) | 2.22 (1.86) | 3.04 (3.95) | 1.100 | 0.977–1.239 | 0.116 |
| CRP (mg/L) | 2.07 (1.77) | 5.05 (8.02) | 1.218 | 1.102–1.345 | <0.001 |
| FEV1 (% predicted) | 77.73±26.05 | 67.59±26.06 | 0.985 | 0.971–1.000 | 0.055 |
| FEV1 (L) | 2.00±0.68 | 1.82±0.75 | 0.689 | 0.391–1.213 | 0.197 |
| FEV1/FVC (%) | 67.07±12.26 | 67.72±11.40 | 1.005 | 0.972–1.038 | 0.785 |
| Proportion of COPD | 46.45% | 72.41% | 3.026 | 1.275–7.185 | 0.012 |
| COPD subjects | |||||
| n | 85 | 21 | |||
| Age, years | 69.13±9.51 | 70.90±7.56 | 1.023 | 0.967–1.082 | 0.426 |
| Gender (male proportion) | 87.06% | 90.48% | 0.708 | 0.145–3.468 | 0.670 |
| Smoking percentage | 88.24% | 90.48% | 1.267 | 0.256–6.270 | 0.772 |
| BMI (kg/cm2) | 22.67±3.35 | 22.52±3.25 | 0.986 | 0.853–1.140 | 0.850 |
| ADAMTS-13 (ng/mL) | 337.91±23.22 | 285.85±20.15 | 0.891 | 0.846–0.937 | <0.001 |
| vWF (ng/mL) | 8.99±1.80 | 10.14±1.14 | 1.525 | 1.105–2.104 | 0.010 |
| MPV (fl) | 11.86±0.80 | 11.67±0.73 | 0.730 | 0.390–1.367 | 0.325 |
| PDW (fl) | 11.02±1.58 | 10.97±1.48 | 0.980 | 0.719–1.337 | 0.900 |
| Fbg (g/L) | 3.93±1.11 | 5.74±2.35 | 2.152 | 1.471–3.149 | <0.001 |
| D-dimer (μg/L) | 294.38 (7.49) | 317.28 (13.12) | 1.126 | 1.071–1.184 | <0.001 |
| IL-6 (pg/mL) | 3.10 (4.15) | 3.19 (4.66) | 1.006 | 0.879–1.151 | 0.934 |
| CRP (mg/L) | 2.22 (2.65) | 8.22 (9.17) | 1.166 | 1.055–1.288 | 0.003 |
| FEV1 (% predicted) | 54.14±15.97 | 55.62±17.79 | 1.006 | 0.976–1.036 | 0.708 |
| FEV1 (L) | 1.67±0.73 | 1.71±0.80 | 1.080 | 0.567–2.057 | 0.815 |
| FEV1/FVC (%) | 57.78±9.33 | 56.57±10.83 | 0.987 | 0.941–1.036 | 1.036 |
Notes: Data are expressed as n; mean ± SD; median (interquartile range); or n (%), unless otherwise stated. Statistical significance (P<0.05) is shown in bold.
Abbreviations: ADAMTS-13, a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13; BMI, body mass index; CRF, chronic renal failure; CRP, C-reactive protein; Fbg, fibrinogen; FEV1, forced expiratory volume in one second; FVC, forced vital capacity; IL-6, interleukin 6; MPV, mean platelet volume; OR, odds ratio; PDW, platelet distribution width; vWF, von Willebrand factor.