Table 1. QPCR Results for M1 macrophages-group composition.
| Gene name | Mean |
M1 |
|
|
|
|
|---|---|---|---|---|---|---|
| p-value | G1 | G2 | G3 | G4 | G5 | |
| ISYNA1 | mean (SD) |
0.39 (1.67) |
0.43 (0.12) |
1.11 (0.41) |
1.66 (0.35) |
1 (0.59) |
| |
P value * |
0.09 |
0.015 |
0.63 |
0.17 |
|
| MRC1 | mean (SD) |
0.45 (0.47) |
1.1 (0.15) |
1.29 (0.72) |
1.35 (0.17) |
1 (0.58) |
| |
P value |
0.4 |
0.48 |
0.5 |
0.28 |
|
| VEGF | mean (SD) |
1.73 (0.38) |
1.08 (0.65) |
0.57 (0.24) |
0.55 (0.28) |
1 (0.43) |
| |
P value |
0.066 |
0.835 |
0.07 |
0.073 |
|
| SOD1 | mean (SD) |
0.76 (0.25) |
0.94 (0.54) |
3.14 (0.82) |
7.0 (0.94) |
1 (0.42) |
| |
P value |
0.55 |
0.48 |
0.0095 |
0.004 |
|
| HMOX1 | mean (SD) |
0.864 (0.1) |
1.29 (0.63) |
24.144 (7.64) |
18.66 (8.67) |
1 (0.49) |
| |
P value |
0.6 |
0.4 |
0.0061 |
0.0025 |
|
| CAT | mean (SD) |
0.74 (0.28 |
0.79 (0.18) |
1.62 (0.39) |
1.6 (0.95) |
1 (0.18) |
| |
P value |
0.5 |
0.7 |
0.11 |
0.26 |
|
| GPX1 | mean (SD) |
2.99 (1.51) |
1.95 (0.98) |
1.22 (0.89) |
1.33 (0.98) |
1 (0.98) |
| P value | 0.16 | 0.4 | 0.66 | 0.17 |
G1: lutein+ zeaxanthin, G2: lutein+ zeaxanthin and zinc, G3: lutein+ zeaxanthin, zinc, Lycomoto and carnosic acid, G4: lutein+ zeaxanthin, carnosic acid and beta- carotene, G5: vehicle control. Genes analyzed included inositol-3-phosphate synthase 1(ISYNA1), mannose receptor C-type 1(MRC1), vascular endothelial growth factor α (VEGF), superoxide dismutase 1(SOD1), heme oxygenase 1(HMOX1), catalase(CAT) and glutathione peroxidase 1(GPX1). * compared to G5 by Mann–Whitney. Gene expression levels represented in RQ values with the control group transformed to 1 and each subsequent group normalized accordingly.