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. Author manuscript; available in PMC: 2018 Dec 10.
Published in final edited form as: J Control Release. 2017 Sep 25;267:100–118. doi: 10.1016/j.jconrel.2017.09.026

Figure 3.

Figure 3

(A) Schematic illustration of mitochondrial targeting of TPP-PEG-L. (B) Mitochondrial colocalization of fluorescently-labeled TPP-PEG-L compared to PL by confocal laser scanning microscopy. HeLa cells were incubated with Rh-PE-labeled TPP-PEG-L and PL for 18 h and then stained with MTG and Hoechst 33342. Yellow spots in the merged pictures denote the co-localization of the liposomes within mitochondrial compartments. a. Images of nuclei stained with Hoechst; b. Mitochondria staining with MTG; c. Uptake of Rh-labeled liposomes; d. Merged picture of all. (Reproduced from ref. [42] with permission)