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. Author manuscript; available in PMC: 2018 Dec 10.
Published in final edited form as: J Control Release. 2017 Sep 5;267:144–153. doi: 10.1016/j.jconrel.2017.09.006

Figure 5. Analysis of nanoparticle co-localization with KR158 cells in vivo.

Figure 5

(A) Bioluminescence image of mouse bearing KR158 intracranial tumor indicated by dotted white circle. (B) H&E (left) and Fn14 (right) staining of KR158 tumor. Fn14 staining is shown in the expanded view of boxed region from H&E stain. (C) Flow cytometry analysis of PLGA-PEG and PLGA-PEG-ITEM4 nanoparticle co-localization in vivo with luciferase-positive KR158 cells in intracranial tumors. Values shown are mean +/− SD (n=3). Data analyzed for significance using Student’s t-test. *P < 0.05.