Levels of sIgD in nasal tissue of CRSsNP. Protein levels of sIgD in A, nasal tissue, B, nasal lavage fluid, and C, serum were measured by using ELISA. The dotted line indicates the threshold based on the 95th percentile of IgD levels in control UT. The individual patient data points are shown, and solid lines represent means ± SEMs. *P < .05, Kruskal-Wallis test.