. Author manuscript; available in PMC: 2018 Dec 1.

Published in final edited form as: J Allergy Clin Immunol. 2017 Jun 16;140(6):1562–1571.e5. doi: 10.1016/j.jaci.2017.05.032

Table 1.

Comparison of clinical features in high-IgD versus low-IgD in nasal tissue from patients with CRS

	High-IgD CRS Patients (n=12)	Low-IgD CRS patients (n=48)	P-value
IgD (ng/mg total protein) in UT, mean (range)	1307 (568.7–4875)	134.1 (5.216–479.8)	*<.0001*
Prevalence of CRSsNP, % (Ratio of CRSsNP:CRSwNP)	75.0% (9:3)	43.7% (21:27)	.05
Purulent rhinorrhea on endoscopy	0%	12.5%	0.33

Medication use (< 4weeks of sinus surgery), %
Antibiotics	33.3%	6.3%	*.01*
Nasal corticosteroids	20.0%	17.2%	.84
Oral corticosteroids	20.0%	33.3%	.42

Asthma,%	41.7%	37.5%	.79
Atopy,%	54.5%	68.3%	.39
ECP (ng/mg total protein), mean (range)	757.4 (1.53–7682)	309.9 (14–1694)	.39
Lund-Mackay score²⁸, mean (range)	10.5 (6–16)	13.0 (3–24)	.09

CRS, chronic rhinosinusitis; UT, uncinate tissue; CRSsNP, chronic rhinosinusitis without nasal polyps; CRSwNP, chronic rhinosinusitis with nasal polyps; ECP, eosinophil cationic protein

Text in boldface indicates statistically significant differences for that variable between high-IgD CRS patients and low-IgD CRS patients (P < .05).