Table 1.

Characteristics of the two consortia

	CPIC	DPWG
Founded	2009	2005
Type of membership	Open for application of new members with a clinical interest in pharmacogenetics, N=206 as of March 2017	By invitation, N=14
Composition	Multidisciplinary	Multidisciplinary
Objectives	1) To address the barriers to implementation of pharmacogenetic tests into clinical practice 2) To provide guidelines that enable the translation of genetic laboratory test results into actionable prescribing decisions for specific drugs	1) To develop pharmacogenetics-based therapeutic (dose) recommendations 2) To assist drug prescribers and pharmacists by integrating the recommendations into computerized systems for drug prescription and automated medication surveillance
Number of gene-drug pairs covered	40	86
Number of gene-drug pairs with therapeutic recommendation	40	47
Frequency of scheduled updates	As needed, reviewed at least every 2 years	If needed, max 4 years
Funding	National Institutes of Health	Royal Dutch Pharmacist’s Association and H2020 contract number 668353-I