Table 2.
CSF Biomarker (model parameter) |
White Matter ROI |
β | Standard Error |
Z- statistic |
95% Confidence Interval |
P- value |
---|---|---|---|---|---|---|
P-tau/Aβ42 (main effect) | Right Cingulum-CC | 0.247 | 0.087 | 2.83 | 0.076, 0.418 | 0.005 |
P-tau/Aβ42 (main effect) | Left Cingulum-CC | 0.282 | 0.103 | 2.74 | 0.080, 0.485 | 0.006 |
YKL-40×time (slope) | Left Cingulum-HC | 0.000310 | 0.000087 | 3.13 | 0.000116, 0.000504 | 0.002 |
CSF=cerebrospinal fluid; ROI=region of interest; p-tau/Aβ42=phosphorylated-tau to beta-amyloid-42 ratio; YKL-40= chitinase-3-like protein. CC=corpus callosum,; HC=hippocampus.