The levels of Nrf2 and its activators [KAP1, p21, p62, p-cJun] and inhibitors [Keap1, Bach1] as well as HO-1 in the kidney of hypertensive rats (A-SHR; B-DOCA-salt) and hypertensive rats after administration of URB597. The expression of the examined proteins is shown compared to the control groups. A. Data points represent the mean ± SD, n = 6; (a, significantly different from WKY group, p < 0.05; b, significantly different from SHR group, p < 0.05). B. Data points represent the mean ± SD; n = 6; (a, significantly different from Wistar group, p < 0.05); b, significantly different from DOCA-salt group, p < 0.05).