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. 2017 Dec 5;8:1687. doi: 10.3389/fimmu.2017.01687

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Copyright © 2017 Pineda, Sigdel, Chen, Jackson, Sirota and Sarwal.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Boxplot representing the distribution of mismatched variants in each D/R pair, stratified by the clinical endpoints of antibody-mediated rejection (AMR), T-cell-mediated rejection (CMR), and no-rejection (NoRej) (A). Principal component analysis plot with the 1,000 G as reference panel (AFR, African population; AMR, American population; EAS, East Asian population; EUR, European population; and SAS, South Asian population). The black dots represent the 28 pairs from our data. Pair 1 shows an example of race mismatch, Pair 14 an example of pair related, and Pairs 12 and 18 an example of a white pair and a black pair, respectively (B).