Skip to main content
. 2017 Dec 5;11:111. doi: 10.3389/fnana.2017.00111

FIGURE 4.

FIGURE 4

The PSB and the growth of the internal capsule (IC). (A–C) Coronal sections through a caudal telencephalic level at 9 GW, and in D–F, through two different levels at 10 GW, show the growing curvature of the lateral ventricle and the opening of the temporal horn at 10 GW. The IC enters the cortex crossing the PSB following a rostral to caudal sequence. While the IC has crossed the PSB at rostral levels (Figure 3E), it has not yet appeared at caudal levels, where PCNA (A) and Tbr2 (C) show mitotic cells at the PSB (indicated by white asterisks), whereas Tbr1 marks the pallial territory (B). (D) At 10 GW, the SVZ of the fronto-parietal PSB and the temporal PSB are connected by a vimentin+ radial glia fascicle (RGF), which is traversed by the IC and delimits the insula. At this time point, the IC has not yet reached the caudal PSB (E), where the SVZ is particularly wide. In F (same level as E), the PSB extends medial to the cortico-striatal sulcus (arrows). GE, ganglionic eminence; I, insula; IC, internal capsule; PC, parietal cortex; SVZ, subventricular zone; T, thalamus; TC, temporal cortex; VZ, ventricular zone. Bars: A–F: 100 μm.