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. 2017 Dec 5;8:2399. doi: 10.3389/fmicb.2017.02399

Table 1.

Parameters for evolutionary rates and Bayesian skyline plot analyses in HuNoV GII.4 and the variants.

Datasets Number of strains Substitutionmodels Clock models Demographic models Chain length of MCMC Log parameter
GII.4 all variants (Complete VP1 gene) 466 GTR+Γ+I Relaxed clock log normal Coalescent exponential population 300,000,000 2,000
Strict clock Coalescent Bayesian skyline 220,000,000 8,000
GII.4 all variants (Shell domain) 466 HKY+Γ+I Strict clock Coalescent exponential population 200,000,000 5,000
GII.4 all variants (P1 domain) 466 SYM+Γ Relaxed clock log normal Coalescent exponential population 210,000,000 2,000
GII.4 all variants (P2 domain) 466 GTR+Γ+I Relaxed clock exponential Coalescent constant population 150,000,000 5,000
US95_96 33 SYM+Γ+I Relaxed clock exponential Coalescent exponential population 250,000,000 2,000
Relaxed clock exponential Coalescent Bayesian skyline 100,000,000 2,000
Farmington Hills 2002 18 K80+Γ Relaxed clock exponential Coalescent exponential population 1,400,000,000 10,000
Relaxed clock exponential Coalescent Bayesian skyline 100,000,000 5,000
Asia 2003 17 K80+Γ Relaxed clock log normal Coalescent exponential population 550,000,000 4,000
Strict clock Coalescent Bayesian skyline 100,000,000 2,000
Hunter 2004 22 K80+Γ Relaxed clock exponential Coalescent exponential population 550,000,000 4,000
Relaxed clock exponential Coalescent Bayesian skyline 100,000,000 2,000
Yerseke 2006a 13 TrNef+Γ Relaxed clock exponential Coalescent exponential population 1,160,000,000 10,000
Relaxed clock exponential Coalescent Bayesian skyline 100,000,000 2,000
Den Haag 2006b 145 HKY+Γ+I Relaxed clock exponential Coalescent exponential population 300,000,000 10,000
Relaxed clock exponential Coalescent Bayesian skyline 300,000,000 10,000
Osaka 2007 11 TrNef+Γ Relaxed clock exponential Coalescent exponential population 100,000,000 2,000
Relaxed clock exponential Coalescent Bayesian skyline 100,000,000 2,000
Apeldoorn 2007 25 TrNef+Γ Relaxed clock exponential Coalescent exponential population 300,000,000 10,000
Relaxed clock exponential Coalescent Bayesian skyline 100,000,000 5,000
New Orleans 2009 86 HKY+Γ+I Random local clock Coalescent exponential population 200,000,000 2,000
Random local clock Coalescent Bayesian skyline 300,000,000 6,000
Sydney 2012 68 TPM2+Γ+I Relaxed clock log normal Coalescent exponential population 100,000,000 5,000
Random local clock Coalescent Bayesian skyline 100,000,000 5,000

Parameters for evolutionary rates and BSP are shown in upper and lower lines, respectively.