Table 1.
The different samples analyzed in the study are listed.
| Sample/MMP | Analysis | 1 | 2 | 3 | 7 | 8 | 9 | 12 | 13 | 14 |
|---|---|---|---|---|---|---|---|---|---|---|
| Mixed cells (whole tissue model) | mRNA | – | – | ✓ | – | nd | (✓) | (✓) | – | – |
| Monocytes/macrophages | ″ | ✓ | – | ✓ | – | nd | – | ✓ | ✓ | – |
| Epithelial cells | ″ | – | – | – | (✓) | nd | – | – | – | – |
| Fibroblasts | ″ | – | – | – | – | nd | – | – | (✓) | – |
| Whole tissue model | IHC | ✓ | nd | ✓ | nd | nd | ✓ | ✓ | nd | nd |
| Lung biopsies | mRNA | (✓) | (✓) | – | (✓) | – | (✓) | (✓) | – | – |
| ″ | IHC | (✓) | nd | (✓) | nd | nd | ✓ | (✓) | nd | nd |
Significant upregulation of individual MMPs are indicated as ✓, more than 3-fold, but not statistically validated upregulation is indicated as (✓). nd, No data, –, not upregulated.