Table 2.

Documentation of GDMT in Patients With HFrEF by Subgroups

	Age, y		Sex		HTN		DM		History of CAD
	<65, N = 11 727	≥65, N = 4143	Male, N = 12 236	Female, N = 3634	Yes, N = 5879	No, N = 9991	Yes, N = 3675	No, N = 12 195	Yes, N = 4329	No, N = 11 541
On ACEI or ARB therapy	32.3	36.9	34.9	28.6	38.8	30.4	44.7	30.1	53.0	26.2
On β‐blocker therapy	33.7	38.3	36.4	29.9	39.6	32.2	46.0	31.6	55.9	27.0
On ACEI or ARB + β‐blocker therapy	28.4	32.9	31.1	24.4	34.6	26.6	41.1	26.1	49.9	22.0

Abbreviations: ACEI, angiotensin‐converting enzyme inhibitor; ARB, angiotensin receptor blocker; CAD, coronary artery disease; DM, diabetes mellitus; GDMT, guideline‐directed medical therapy; HFrEF, heart failure with reduced ejection fraction; HTN, hypertension.

Data are presented as %.

The P value comparing use of all GDMT within each subgroup was <0.001.