Skip to main content
. 2017 Dec 6;11:578. doi: 10.3389/fnhum.2017.00578

Figure 3.

Figure 3

Effects of COMT genotype and sex on network activation during a delay discounting task. (A) Activation of each network is plotted by COMT genotype and sex. For display purposes, beta estimates of task-related activation for all ROIs of a given network are averaged. Error bars reflect standard errors of the mean. (B) Scatter plot of task activation effects plotted against COMT genotype × sex interaction effects on each of the 264 ROIs, color coded by association with large-scale networks. Symbols on the y-axis correspond with the direction of interaction effects, producing u-shaped (positive values) or inverted u-shaped (negative values) relationships. (*) Denotes statistically significant COMT genotype × sex interaction effect measured at the network level. AU, auditory; CE, cerebellar; CO, cingulo-opercular task control; DM, default mode; DA, dorsal attention, FP, fronto-parietal task control; ME, memory retrieval; SA, salience; SML, lateral sensorimotor; SMM, medial sensorimotor; SC, subcortical; VA, ventral attention; VI, visual.