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. 2017 Dec 6;8:1734. doi: 10.3389/fimmu.2017.01734

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Copyright © 2017 Duan, Rao, Braunstein, Toomey and Zhong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The regulatory role of dipeptidyl peptidase-4 (DPP-4)/glucagon-like peptides (GLPs) in gut immunity: DPP-4/GLP axis regulates gut inflammation through (1) promoting the tissue repair of injured epithelium, (2) regulating the differentiation and functions of Treg and intraepithelial lymphocytes, and (3) regulating the function of macrophages and dendritic cells.