Table 2. Top 25 genes associated with inflammatory Δage.
| Affymetrix Transcript Cluster ID | Gene | Beta | SE | P-value |
|---|---|---|---|---|
| 2357845 | FCGR1A | 0.0154 | 0.0014 | 3.5E-26 |
| 2636626 | GRAMD1C | −0.0098 | 0.0011 | 1.3E-19 |
| 3527514 | PNP | 0.0094 | 0.0011 | 8.1E-18 |
| 3161082 | CD274 | 0.0140 | 0.0016 | 1.1E-17 |
| 3696142 | DPEP2 | −0.0051 | 0.0006 | 2.6E-17 |
| 3157660 | TSTA3 | 0.0101 | 0.0012 | 4.4E-17 |
| 3941793 | KREMEN1 | 0.0071 | 0.0008 | 9.3E-17 |
| 2951730 | SLC26A8 | 0.0062 | 0.0007 | 1.2E-16 |
| 4009849 | ALAS2 | 0.0152 | 0.0019 | 9.6E-16 |
| 3709685 | NDEL1 | −0.0040 | 0.0005 | 1.9E-15 |
| 3061456 | SAMD9L | 0.0093 | 0.0012 | 2.1E-15 |
| 3576284 | RPS6KA5 | −0.0049 | 0.0006 | 3.0E-15 |
| 3690550 | SIAH1 | −0.0046 | 0.0006 | 3.2E-15 |
| 2421925 | GBP7 | 0.0054 | 0.0007 | 5.1E-15 |
| 2700828 | SIAH2 | 0.0052 | 0.0007 | 9.1E-15 |
| 2584258 | KCNH7 | 0.0043 | 0.0005 | 1.1E-14 |
| 3628832 | DAPK2 | −0.0048 | 0.0006 | 1.1E-14 |
| 2828479 | SLC22A4 | 0.0056 | 0.0007 | 2.0E-14 |
| 2369463 | FAM20B | 0.0055 | 0.0007 | 2.5E-14 |
| 2964200 | UBE2J1 | 0.0052 | 0.0007 | 5.2E-14 |
| 3090053 | SLC25A37 | 0.0094 | 0.0012 | 6.5E-14 |
| 2438531 | HDGF | 0.0065 | 0.0009 | 9.6E-14 |
| 3651955 | METTL9 | 0.0054 | 0.0007 | 1.1E-13 |
| 2421883 | GBP1 | 0.0098 | 0.0013 | 1.4E-13 |
| 2909404 | CD2AP | 0.0066 | 0.0009 | 1.4E-13 |
+The analyses were adjusted for age and sex
*Beta is in units of one standard deviation change in gene expression per year of inflammatory Δage; *SE: standard error