Table 3. Comparison of the concentration of PPAR-γ, MMP-9 and TIMP-1 in the inducing sputum in COPD patients with or without emphysema.
Variables | Emphysema group | Non-emphysema group | P |
---|---|---|---|
FEV1 (L) | 1.06±0.40 | 1.27±0.50 | 0.080 |
FEV1%Pred | 40.32±14.19 | 49.99±12.41 | 0.007 |
RV (L) | 4.58±1.16 | 3.77±1.18 | 0.009 |
RV% | 199.90±47.95 | 167.13±45.90 | 0.011 |
CAT | 26.23±13.03 | 16.15±6.08 | 0.030 |
PPAR-γ (ng/L) | 114.63±19.55 | 127.87±27.00 | 0.031 |
TIMP1 (U/L) | 83.28±15.12 | 99.68±12.54 | <0.001 |
MMP9 (μg/L) | 20.44±8.99 | 15.91±5.66 | 0.021 |
MMP9/TIMP1 | 0.26±0.13 | 0.16±0.06 | 0.001 |